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    NIAID FWD IRN ANIMAL MODEL WORKSHOP
    Final Agenda
    April 26-28, 2005
    National Food Safety and Toxicology Center
    Michigan State University
    East Lansing, Michigan
    Objectives
  • Gain insights from invited experts into what characteristics are necessary for a good animal model for pathogenesis studies.
  • Priority animal models: noroviruses, HUS, Shigella, IBD.
  • Report and update progress on FWD IRN projects, especially those involved with animal model utilization and development.
  • Identify reagents and resources that can be shared among FWD IRN units.
  • Describe, prioritize, and coordinate future directions and research projects for the FWD IRN.
    • Final Agenda
    Tuesday, April 26, 2005
    7:00 PMInformal welcoming dinner
    (State Room, Kellogg Hotel and Conference Center)
    Wednesday, April 27, 2005
    7:15 AMDeparture from hotel lobby to National Food Safety and Toxicology Center (NFSTC)
    7:30 AM to 8:00 AMContinental breakfast, NFSTC Building Cafeteria
    8:00 AM to 8:10 AMWelcome
    Dr.Thomas Whittam, Dr. Clare Schmitt
    8:10 AM to 9:50 AMSession 1. Moderator: Dr. Linda Mansfield (MRU-Michigan State University)
    8:10 AM to 9:00 AMChallenges and considerations in developing animal models for biothreats
    Dr. Rick Lyons (University of New Mexico)
    9:00 AM to 9:50 AMGnotobiotic piglets as a model for human enteric diseases
    Dr. Saul Tzipori (MBRU-Tufts University)
    10:00 AM to 10:15 AMCoffee break
    10:20 AM to 12:15 PMSession 2. Moderator: Dr. Saul Tzipori (MBRU-Tufts University)
    10:20 AM to 11:10 AMAnalysis of Campylobacter jejuni colonization in a chick model
    Dr. Victor DiRita (University of Michigan)
    11:15 AM to 11:45 AMRabbit models of HUS
    Dr. Edgar Boedeker (MRU-University of Maryland)
    11:45 AM to 12:15 PMExperimental infection of alpha-galactosidase knockout mice with EHEC
    Dr. Vincent Young (MRU-Michigan State University)
    12:30 PM to 1:25 PMLunch
    1:30 PM to 3:40 PMSession 3. Moderator: Dr. Marcelo Sztein (IRU-University of Maryland)
    1:30 PM to 2:20 PMRole of intestinal flora in development of B cell and antibody repertoires
    Dr. Katherine Knight (Loyola University)
    2:20 PM to 2:50 PMIL-10 knockout mouse model for Campylobacteriosis
    Dr. Linda Mansfield (MRU-Michigan State University)
    2:50 PM to 3:10 PMBreak
    3:10 PM to 3:40 PMRabbit model of tularemia vaccination
    Dr. Marcelo Sztein (IRU-University of Maryland)
    3:45 PM to 5:30 PMBreakout and discussion
    7:00 PMDinner
    (Meet in hotel lobby at 7:00 pm)
    Thursday, April 28, 2005
    7:15 AMDeparture from hotel lobby to Diagnostic Center for Population and Animal Health (DCPAH)
    7:30 AM to 8:00 AMContinental breakfast, DCPAH
    8:00 AM to 8:15 AMWelcome to DCPAH
    Dr. Willie Reed (DCPAH)
    8:15 AM to 10:10 AMSession 4. Moderator: Dr.Yrjö Gröhn (ZRU-Cornell University)
    8:15 AM to 9:05 AMMicroaerobes, Models and Malignancy
    Dr. James Fox (Massachusetts Institute of Technology)
    9:10 AM to 9:40 AMBovine models of EHEC colonization and transmission
    Dr. Tom Besser (ZRU-Washington State University)
    9:40 AM to 10:10 AMNewborn calf model of ETEC infection
    Dr. Mahdi Saeed (MRU-Michigan State University)
    10:15 AM to 10:30 AMCoffee break
    10:30 AM to 11:30 AMBreakout and discussion
    11:30 AM to 12:15 PMTour of DCPAH
    Dr. Steve Bolin
    12:30 PM to 1:30 PMLunch, NFSTC
    Departure
    Contact stec@cvm.msu.edu
    Operated by the Microbial Evolution Laboratory at Michigan State University
    National Institutes of Health (NIH)
    9000 Rockville Pike
    Bethesda, Maryland 20892     		National Institute of Allergy and Infectious Diseases
    6610 Rockledge Drive, MSC 6612
    Bethesda, MD 20892-6612     		Food and Waterborne Diseases Integrated Research Network